SYNTHESIS OF BILE ACIDS AND BILE SALTSGenes with highest essentiality change:
ACOX2
CYP8B1
CYP7A1
AKR1C4
Genes with specificity change:
ACOT8
Oncoprint [mutation]
norm mutation data
ph mutation data
Legend
Condition
— norm specific
— ph specific
— Both
Interaction
-- Statistical dependency
— Known interaction
RNA Expression
• High
• Intermediate
• Low
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