CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6

Genes with highest essentiality change: RPS27A PSMA5 PSMD9 PSME2 PSME1 PSMD8 PSMD7 PSMD4 PSMD3 PSMD13 PSMD11 PSMC3 PSMC2 PSMC1 PSMB9 PSMB7 PSMB5 PSMB3 PSMB2 PSMB1 PSMB10 PSMA7 PSMA6 PSMA4 PSMA3 PSMA2 PSMF1 PSMD5

Genes with specificity change: CDK2 PSMD12 PSMB6 PSMB8 PSME4

Oncoprint [mutation]

norm mutation data

ph mutation data

Legend
    Condition
    — norm specific
    — ph specific
    — Both
    Interaction
    -- Statistical dependency
    — Known interaction
    RNA Expression
    • High
    • Intermediate
    • Low
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